So, if I intend to leave my current company in a year & move my 401K into another 401K or IRA option, does it make sense to just keep everything in a money market fund? Would I have to stay with the same funds for 5 or more years to reap any benefits from the stock market? Thanks.
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The UFC lightweight champion Benson Henderson held onto his belt with a dominating performance over Nate Diaz at the Key Arena in Seattle on Saturday night. Henderson took the five-round bout 50-43, 50-45, 50-45. Henderson landed 133 significant strikes throughout the bout.
Henderson set the tone early when he got a takedown and stood over Diaz before landing shots. Throughout the round, Henderson peppered Diaz with leg kicks. It caused damage early and throughout the bout.
Diaz showed signs of life in the third round with leg lock and heel hook submission attempts. Both ?times Henderson was able to get out. Late in the round, he dropped Diaz, who continued to try for leg submissions.
At the end of the fourth round, Henderson jumped around and showed how fresh he was while Diaz had to get his eyes checked by the fight doctor. Henderson had a big takedown in the fifth, and continued to control Diaz throughout the round.
When the fight was over, Henderson reportedly walked over towards the media on press row and shouted to them:
"I don't talk, it's in here. Do you guys get it?"
This was Henderson's second title defense. He is undefeated since joining the UFC and has a record of 17-2. His last two bouts were razor-close decisions, but with this fight, Henderson has a signature performance to show he is deserving of the UFC's shiny, gold belt.
Going into this fight, Diaz had three wins at lightweight. Two were by submission, but his submission skills didn't work on Henderson. Diaz falls to an overall record of 16-8.
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December 7, 2012
A $243 million renovation of the St. Paul Union Depot is completed, and the downtown St. Paul facility will reopen to transit riders on Saturday, kicked off with an open house for the public. Here's a look at the depot from a historical perspective.
1
St. Paul, Minnesota, USA ? St. Paul Union Depot construction in 1919. (Courtesy of Minnesota Historical Society) link to this photo
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St. Paul, Minnesota, USA ? View of the St. Paul railroad yard showing Great Northern train in 1931. (Courtesy of Minnesota Historical Society) link to this photo
3
St. Paul, Minnesota, USA ? Passengers at the St. Paul Union Depot in 1936. (Courtesy of Minnesota Historical Society) link to this photo
4
St. Paul, Minnesota, USA ? St. Paul Union Depot 1924-1925. (Courtesy of Minnesota Historical Society) link to this photo
5
St. Paul, Minnesota, USA ? Passengers waiting to board trains at St. Paul's Union Depot in 1949. (Courtesy of Minnesota Historical Society) link to this photo
6
St. Paul, Minnesota, USA ? School children on a platform at the St. Paul Union Depot view the streamlined locomotive of the Burlington Zephyr in 1949. (Courtesy of Minnesota Historical Society) link to this photo
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St. Paul, Minnesota, USA ? People lined up for Easter Sunday dinner at the Union Depot restaurant in St. Paul, Minn. in 1962. (Courtesy of Minnesota Historical Society) link to this photo
8
St. Paul, Minnesota, USA ? "Railroad Day" celebration inside the St. Paul Union Depot in 1948. (Courtesy of Minnesota Historical Society) link to this photo
9
St. Paul, Minnesota, USA ? St. Paul Union Depot concourse in 1948. (Courtesy of Minnesota Historical Society) link to this photo
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This panorama shows the new interior of the Union Depot. The landmark station reopens Saturday after a $243 million face-lift and will host a new bus hub. St. Paul hopes the depot can spark a transportation renaissance for the city. (MPR Photo/Tim Nelson) link to this photo
Source: http://minnesota.publicradio.org/display/web/2012/12/07/union-depot-historical-photos/?refid=0
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In each of our cells, most of the genetic material is packaged safely within the nucleus, which is protected by a double membrane. The biochemistry behind how this membrane transforms when cells divide has finally been unravelled, offering insights that could provide new ways of fighting cancer and some rare genetic disorders.
During cell division, the membrane that surrounds the nucleus breaks down and reforms in the two daughter cells. Researchers have been split on the precise mechanisms that govern membrane reformation. One view is that proteins alone control the membrane's transformations. Another possibility is that changes in lipids ? a vast group of fat-related compounds ? are responsible.
Experiments had failed to show which of these two ideas was right, because it was difficult to alter lipid levels in specific compartments of cells without affecting other cellular processes.
Banafshe Larijani at Cancer Research UK's London Research Institute and her colleagues have now overcome that hurdle. They came up with a technique that transforms a type of lipid called a diacylglycerol (DAG) into another lipid, within the nuclear membrane.
The technique involves inserting two fragments of DNA into the nucleus of a cell. This causes the cell to make two proteins: the first attaches itself to the nuclear membrane, the second floats around the cell. Adding a drug ? rapalogue ? to the mix causes the second protein to stick to the first, which in turn causes a chemical cascade that transforms the DAG into a different kind of lipid.
Crucially, they targeted a form of DAG that does not bind to proteins, so converting it into a different lipid does not affect any processes involving proteins in the cell.
The team tested the effect of this lipid manipulation on cell division in monkey and human cancer cells. The lower the level of DAG present in the nuclear membrane, the greater the membrane malformation and chance of cell death.
This demonstrates that lipids play a role in nuclear membrane reformation that does not depend on proteins.
Larijani says it "opens the door to finding ways to kill cancerous cells" by focusing on lipids that are important to the nuclear membrane's development.
As the nucleus divides, sausage-shaped fragments of its membrane float around the cell. The fragments have curved ends, and Larijani says that changes in lipid composition generate these curves, without which the fragments cannot reassemble correctly into new membranes.
More than a dozen rare genetic conditions such as Hutchinson-Gilford progeria syndrome, which is characterised by premature ageing in children, have been linked to irregularities in cell division. A better understanding of the way the nuclear membrane forms when cells divide could be key to treating these disorders.
The research also offers a new focus for preventing the irregular cell division that underlies many cancers.
"As a result of this work we now know with confidence that DAG plays a structural role in membrane dynamics," says Vytas Bankaitis, at the Texas A&M Health Science Center in College Station, who was not involved in the study. "If we could find a molecule with suitable characteristics, this manipulation could be done [in humans], which is something that has not really been considered before."
Journal reference: PLoS ONE, DOI: 10.1371/journal.pone.0051150
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Erin Purchase and Brandon Krenzler, parents of "Brave Mykayla," a 7-year-old with leukemia, told HuffPost Live host Alyona Minkovski on Friday why and how they treat their child's symptoms with medicinal marijuana.
Purchase described the effect of cannabis oil on her daughter's condition.
"She has no pain, she's happy, she eats, she hasn't lost weight, and she doesn't take a lot of medications at home, basically none," she said.
Purchase explained why she was interested in trying an alternative medical approach.
"I know how bad pharmaceutical medications can be for the human body and how toxic they are on top of chemotherapy, and I was interested in using the most natural way to treat my daughter as possible," she said.
Watch the full segment at HuffPost Live.
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Source: http://www.huffingtonpost.com/2012/12/03/medical-marijuana-helping_n_2233016.html
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Source: http://vansegitseg.neobase.hu/bejegyzes/casheminutecardepaydayeloansesimpleandeasyesafeguarded
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Food Vendor Applications Now Available
Applications for food vendors (including food trucks and carts) are now available for the Columbus Arts Festival presented by Time Warner Cable, June 7, 8 & 9, 2013. Located along the Scioto Mile at the Downtown Riverfront, the Festival area encompasses Bicentennial Park and the Main and Rich Street bridges. Great food is one of the highlights of the Festival and approximately 400,000 art and food lovers attend each year.? Follow this link http://columbusartsfestival.org/contact/press-room/2013-food-vendor-apps.php to read the full press release.
Poet Applications Are Now Available
Columbus has some of the most talented spoken word artists in the country and the Columbus Arts Festival features the best of the best each year. Poets chosen through an audition process will have an exciting opportunity to share their work at appointed times on Friday through Sunday of the festival in the Word is Art tent?a location dedicated to poetry performance. Follow this link http://columbusartsfestival.org/contact/press-room/2013-poetry-apps.php to read the full press release.
Caricaturist, Portrait Artist, TemporaryTattoo/Henna Artists Applications Now Available
Each year the Festival seeks accomplished individuals to submit work for selection as on site caricature artists, charcoal artists, face painters and temporary tattoo/henna artists.
Chosen participants will be appointed spaces throughout the festival.? Follow this link http://columbusartsfestival.org/contact/press-room/caricature-artist-application.php to read the full press release.
Edited by Columbus Post staff.
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